Nestlets by Ancare

Manufactured from pulped virgin cotton fiber, sterilized during manufacture and clean packed. Fully autoclavable, Nestlets are sufficiently pathogen-free for all purposes except gnotobiotic. Nestlets will not deteriorate in storage and are packed in extra-strength polyethylene bags. Shipped in dust proof, sturdy cartons.

Rodents are nesting animals. Investigation has well established that when they are able to build nests, rodents are less disturbed by sound, light, motion and temperature changes. The protective, insulating qualities of a nest reduces animal loss. Nests also lend a greater sense of security and, being more tranquil, animals are less aggressive, fight less, are easier to handle, and cannibalism is reduced. This reduction in stress results in greater weight gain, healthier and happier animals and more valid models for research.

The 8th edition of the Guide for the Care and Use of Lab Animals endorses the use of nesting materials to aid in thermoregulation;

The ambient temperature range in which thermoregulation occurs without the need to increase metabolic heat production or activate evaporative heat loss mechanisms is called the thermoneutral zone (TNZ) and is bounded by the lower and upper critical temperatures (LCTs and UCTs; Gordon 2005). To maintain body temperature under a given environmental temperature animals adjust physiologically (including their metabolism) and behaviorally (including their activity level and resource use). For example, the TNZ of mice ranges between 26°C and 34°C (Gordon 1993); at lower temperatures, building nests and huddling for resting and sleeping allow them to thermoregulate by behaviorally controlling their microclimate. Although mice choose temperatures below their LCT of 26°C during activity periods, they strongly prefer temperatures above their LCT for maintenance and resting behaviors (Gaskill et al. 2009; Gordon 2004; Gordon et al. 1998). Similar LCT values are found in the literature for other rodents, varying between 26-30°C for rats and 28-32°C for gerbils (Gordon 1993). The LCTs of rabbits (15-20°C; Gonzalez et al. 1971) and cats and dogs (20-25°C) are slightly lower, while those of nonhuman primates and farm animals vary depending on the species. In general, dry-bulb temperatures in animal rooms should be set below the animals’ LCT to avoid heat stress. This, in turn, means that animals should be provided with adequate resources for thermoregulation (nesting material, shelter) to avoid cold stress. Adequate resources for thermoregulation are particularly important for newborn animals whose LCT is normally considerably higher than that of their adult conspecifics.

The Perfect Nesting Material

In harmony with the natural instincts of mice, Nestlets retain warmth without obstructing airflow or humidity dissipation. Inert and non-ingestible, Nestlets will not compact or form threads or ligatures. They are soft and absorbent, non-irritating even to newborn young.

Shred and Build

Nestlets utilize the inherent instinct of rodents to shred and build nests with any material available. The act of shredding is a natural occupation, and exercise, therefore beneficial.

Pennies Per Cage

We all need to keep an eye on expenditures, so you can rest assured that Nestlets maintain the best possible value/cost ratio of any other Environmental Enrichment available to the industry today.

Clean, dust-free, economical and autoclavable, the one and only Nestlets™ are available from the one and only Ancare.